Grupos de Investigación
Sede Chascomús

Laboratorio de Fotoquímica y Fotobiología Molecular

Integrantes

Directores:
Dr. Franco M. Cabrerizo
Investigador Independiente CONICET

Profesor Asociado UNSAM

email: fcabrerizo@intech.gov.ar
Dra. M. Paula Denofrio
Investigador Adjunto CONICET

Profesor Adjunto UNSAM

email: pdenofrio@intech.gov.ar
Miembros actuales:
Dra. M. Micaela Gonzalez (Investigadora Asistente-CONICET, Prof. Adjunto-UNSAM)

Dra. M. Lis Alomar (Investigadora Asistente-CONICET)

Dr. Fabricio Ragone (Becario Postdoctoral CONICET)

Lic. Gabriel Yañuk (Becario Doctoral CONICET)

Lic. Ivan Maisuls (Becario Doctoral CONICET)

Lic. Mariangeles Carra (Becario Doctoral CONICET)

Ing. Fernando Villarruel (Becario Doctoral ANPCyT)

Sr. Carlos G. Alberici (Técnico Asociado-CPA CONICET)
Ex-Integrantes:
Dra. Karina Levy (Becaria Postdoctoral CONICET; 2013-2015 Investigadora Asistente-CONICET; 2015-2016)

Dra. Mariana Vignoni (Postdoctorado; 2012-2013)

Dr. Federico A. O. Rasse-Suriani (Becario Doctoral CONICET; 2011-2016)

Matías Alés-Gandolfo (Tesina de grado; 2011)

Ing. Fernando Villarruel (Tesina de grado, 2016)

Ing. Francisco Simon (Tesina de grado, 2016)

Líneas de investigación

Publicaciones

2016-2017
  1. Chemical and photochemical properties of chloroharmine derivatives in aqueous solutions. Federico A. O. Rasse-Suriani, M. Paula Denofrio, Juan G. Yañuk, M. Micaela Gonzalez, Ezequiel Wolcan, Marco Seifermann, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Phys. Chem. Chem. Phys., 2016, 18, 886-900. ISSN: 1463-9076
  2. Albumin-folate-conjugates for drug-targeting in photodynamic therapy. Kathrin Butzbach, Federico A. O. Rasse-Suriani, M. Micaela Gonzalez, Franco M. Cabrerizo* and Bernd Epe*. Photochem. Photobiol., 2016, 92, 611-619. ISSN: 0031-8655.
  3. Propiedades fotosensibilizadoras de β-carbolinas: daño al ADN en condiciones intra- y extracelulares. Franco M. Cabrerizo*, M. Micaela Gonzalez, Mariana Vignoni, M. Paula Denofrio y Rosa Erra-Balsells. Anales Acad. Nac. de Cs. Ex., Fís. y Nat., 2016, tomo 67, 41-62. ISSN: 2451-8182.
  4. Antifungal activity of β-carbolines on Penicillium digitatum and Botrytis cinerea. Gabriela M. Olmedo, Luciana Cerioni, Micaela M. González, Franco M. Cabrerizo, Viviana A. Rapisarda, Sabrina I. Volentini*. Food Microbiology, 2017, 62, 9 - 14. ISSN: 0740-0020.
  5. A cockspur for the DSS cells: Erythrina crista-galli sensitizers. Paula Enciso, Jean-David Decoppet, Michael Grätzel, Michael Wörner, Franco M. Cabrerizo and María Fernanda Cerdá. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2017, 176, 91–98. ISSN: 1386-1425.
  6. UVA Photoactivation of Harmol Enhances Its Antifungal Activity against the Phytopathogens Penicillium digitatum and Botrytis cinerea. Gabriela M. Olmedo, Luciana Cerioni, Micaela M. González, Franco M. Cabrerizo, Sabrina I. Volentini, Viviana A. Rapisarda*. Frontiers in Microbiology, 2017, 8, doi: 10.3389/fmicb.2017.00347. ISSN: 1664-302X.
  7. Photophysical and photochemical properties of naturally occurring normelinonine F and melinonine F alkaloids and structurally related N(2)- and/or N(9)-methyl-β-carboline derivatives. Federico A. O. Rasse-Suriani, Fernando S. García-Einschlag, Matías Rafti, Tobías Schmidt De León, Pedro M. David Gara, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Photochemistry and Photobiology, 2017, ISSN: 0031-8655.
2014-2015
  1. Intra- and extracellular DNA damage by harmine and 9-methyl-harmine. Mariana Vignoni, Rosa Erra-Balsells, Bernd Epe* and Franco M. Cabrerizo*. Journal of Photochemistry and Photobiology. B: Biology, 2014, 132, 66-71. ISSN: 1011-1344.
  2. Comment on “Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach”. Maria L. Alomar, M. Micaela Gonzalez, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Journal of Photochemistry and Photobiology. B: Biology, 2014, http://dx.doi.org/10.1016/j.jphotobiol. 2014, 136, 26-28. ISSN: 1011-1344.
  3. Selective quenching of triplet excited states of pteridines. M. Paula Denofrio, Peter R. Ogilby, Andrés H. Thomas and Carolina Lorente. Photochemical and Photobiological Sciences, 2014, 13(7):1058-65. ISSN: 1474-905X.
  4. Determining the Molecular Basis for the pH-dependent Interaction among 2´-deoxynucleotides and 9H-pyrido[3,4-b]indole in its ground and excited electronic states. M. Micaela Gonzalez, M. Paula Denofrio, Fernando S. García Einschlag, Carlos A. Franca, Reinaldo Pis Diez, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Phys. Chem. Chem. Phys., 2014, 16, 16547-16562. ISSN: 1463-9076.
  5. Experimental and computational study of solvent effects on one- and two-photon absorption spectra of chlorinated harmines. Dalibor Hršak, Lotte Holmegaard, Anton S. Poulsen, Nanna H. List, Jacob Kongsted, M. Paula Denofrio, Rosa Erra-Balsells, Franco M. Cabrerizo*, Ove Christiansen* and Peter R. Ogilby*. Phys. Chem. Chem. Phys.,2015, 17, 12090-12099. .
  6. DNA damage induced by bare and loaded Microporous Coordination Polymers from their ground and electronic excited states. Juan G. Yañuk, María L. Alomar, M. Micaela Gonzalez, Francisco Simon, Rosa Erra-Balsells, Matías Rafti,* and Franco M. Cabrerizo*. Phys. Chem. Chem. Phys., 2015, 17, 12462-12465
  7. Norharmane Rhenium(I) polypyridyl complexes: Synthesis, structural and spectroscopic characterization. Iván Maisuls, Ezequiel Wolcan, Oscar E. Piro, Gustavo A. Echeverría, Gabriela Petroselli, Rosa Erra-Balsells, Franco M. Cabrerizo* and Gustavo T. Ruiz*. Dalton Trans., 2015, 44, 17064-17074.
2012-2013
  1. "Mechanism of electron-transfer processes photoinduced by lumazine" M. Paula Denofrio, M. Laura Dántola; PatriciaVicendo; Esther Oliveros Andrés H. Thomas and Carolina Lorente. Photochem. Photobiol. Sci, 2012, 11, 409-417
  2. Photosensitization of DNA by β-carbolines: Kinetic analysis and photoproducts characterization. M. Micaela Gonzalez, Mariana Vignoni, Magali Pellon-Maison, Matías A. Ales-Gandolfo, M. del Rosario Gonzalez-Baró, Rosa Erra-Balsells, Bernd Epe* and Franco M. Cabrerizo*. Organic and Biomolecular Chemistry, 2012, 10, 1807-1819. ISSN: 1477-0520
  3. Characterization and reactivity of photodimers of dihydroneopterin and dihydrobiopterin. Mariana Vignoni, Carolina Lorente, Franco M. Cabrerizo, Rosa Erra-Balsells, Esther Oliveros and Andrés H. Thomas. Photochemical & Photobiological Sciences, 2012, 11 (6), 979 - 987. ISSN: 1474-905X
  4. Photosensitized electron transfer within self-assembled norharmane-2'-deoxyadenosine 5'-monophosphate (dAMP) complex. M. Micaela Gonzalez, Federico A. O. Rasse-Suriani, Carlos A. Franca, Reinaldo Pis Diez, Yousef Gholipour, H. Nonami, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Organic and Biomolecular Chemistry, 2012, 10, 9359-9372. ISSN: 1477-0520
  5. Rhenium(I)-Pterin water-soluble complex: Synthesis and structural characterization. Two reversible protonation-deprotonation behavior in aqueous solutions. F. Ragone, G. T. Ruiz*, O. E. Piro, G. A. Echeverría, F. M. Cabrerizo, G. Petroselli, R. Erra-Balsells, K. Hiraoka, F. García Einschlag and E. Wolcan*. European Journal of Inorganic Chemistry, 2012, 4801-4810. ISSN: 1434-1948
  6. In vitro evaluation of β-carbolines alkaloids as potential anti-Toxoplasma agents. Maria L. Alomar; Federico A. O. Rasse-Suriani, Agustina Ganuza, Verónica M. Coceres, Franco M. Cabrerizo* and Sergio O. Angel*. BMC Research Notes, 2013, 6, 193.
  7. Mechanisms of DNA damage by photoexcited 9-methyl-β-carbolines. Mariana Vignoni, Federico A. O. Rasse-Suriani, Kathrin Butzbach, Rosa Erra-Balsells, Bernd Epe* and Franco M. Cabrerizo*. Organic and Biomolecular Chemistry, 2013, , 11, 5300-5309. ISSN: 1477-0520.
  8. Phycocyanin as potential natural dye for use in photovoltaic cells. Paula Enciso, Franco M. Cabrerizo, Jorge Gancheff, Pablo Denis and María Fernanda Cerdá*. J. App. Sol. Chem. Model., 2013, 2, 225-233
2010-2011
  1. Photochemistry of dihydrobiopterin in aqueous solution. Mariana Vignoni, Franco M. Cabrerizo, Carolina Lorente, Nathalie Martins-Froment, Esther Oliveros* and Andrés H. Thomas*. Organic and Biomolecular Chemistry, 2010, 8, 800-810. ISSN: 1477-0520
  2. 1H-NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions. Mariana Vignoni, M. Laura Salum, Rosa Erra-Balsells, Andrés H. Thomas* and Franco M. Cabrerizo*. Chemical Physics Letters, 2010, 484, 330-332. ISSN: 0009-2614
  3. Fluorescence Quenching by Oxygen: "Debunking" a Classic Rule. Franco M. Cabrerizo,* Jacob Arnbjerg, M. Paula Denofrio, Rosa Erra-Balsells, and Peter R. Ogilby*. ChemPhysChem., 2010, 11 (4), 796-798. ISSN: 1439-7641
  4. Photosensitized Cleavage of Plasmidic DNA by Norharmane, a Naturally Occurring β-carboline. M. Micaela Gonzalez, Magali Pellon-Maison, Matias A. Ales-Gandolfo, Maria R. Gonzalez-Baró, Rosa Erra-Balsells* and Franco M. Cabrerizo*. Organic and Biomolecular Chemistry, 2010, 8, 2543 - 2552, ISSN: 1477-0520
  5. Photodynamic Effects of Pterin on HeLa Cells. M. Paula Denofrio, Carolina Lorente, Thomas Breitenbach, Sonja Hatz, Franco M. Cabrerizo*, Andrés H. Thomas* and Peter R. Ogilby*. Photochemistry and Photobiology, 2011, 87, 862–866. ISSN: 0031-8655
2008-2009
  1. Oxidation of 2'-deoxyguanosine-5'-monophosphate photoinduced by pterin: type I versus type II mechanism. Gabriela Petroselli, M. Laura Dántola, Franco M. Cabrerizo, Alberto L. Capparelli, Carolina Lorente, Esther Oliveros* y Andrés H. Thomas*. Journal of American Chemical Society, 2008, 130 (10), 3001-3011. ISSN: 0002-7863
  2. New results on the photochemistry of biopterin and neopterina in aqueous solution. Mariana Vignoni, Franco M. Cabrerizo, Carolina Lorente y Andrés H. Thomas*. Photochemistry and Photobiology, 2009, 85, 365-373. ISSN: 0031-8655
  3. Quenching of the fluorescence of aromatic pterins by deoxynucleotides. Gabriela Petroselli, M. Laura Dántola, Franco M. Cabrerizo, Carolina Lorente, André M. Braun, Esther Oliveros*, Andrés H. Thomas*. Journal of Physical Chemistry A, 2009, 113 (9), 1794–1799. ISSN: 1089-5639
  4. Predictive Modeling of the Total Deactivation Rate Constant of Singlet Oxygen by Heterocyclic Compounds. Andrew G Mercader*, Pablo R. Duchowicz, Francisco M. Fernández, Eduardo A. Castro, Franco M. Cabrerizo and Andrés H. Thomas. Journal of Molecular Graphics and Modelling, 2009, 28, 12-19. ISSN: 1093-3263
  5. One- and two-photon excitation of β-carbolines in aqueous solution: pH-dependent spectroscopy, photochemistry and photophysics. M. Micaela Gonzalez, Jacob Arnbjerg, M. Paula Denofrio, Rosa Erra-Balsells, Peter R. Ogilby* and Franco M. Cabrerizo*. Journal of Physical Chemistry A, 2009, 113 (24), 6648 – 6656; ISSN: 1089-5639
  6. Photochemistry of norharmane in aqueous solution. M. Micaela Gonzalez, M. Laura Salum, Yuosef Gholipour, Franco M. Cabrerizo* and Rosa Erra-Balsells*. Photochem. Photobiol. Sci., 2009; 8, 1139–1149; ISSN: 1474-905X
  7. Study of photosensitizing activity of lumazine using a 2´-deoxyguanosine 5´-monophosphate and HeLa cells as targets. M. Paula Denofrio, Sonja Hatz, Carolina Lorente, Franco M. Cabrerizo*, Peter R. Ogilby* and Andres H. Thomas*. Photochem. Photobiol. Sci., 2009, 8, 1539-1549. ISSN: 1474-905X
2006-2007
  1. Photoinduced Formation of Reactive Oxygen Species from the Acid Form of 6-(Hydroxymethyl)pterin in Aqueous Solution. Andrés H. Thomas, Romina Cabrerizo, Mariana Vignoni, Rosa Erra-Balsells, Franco M. Cabrerizo* and Alberto L. Capparelli*. Helvetica Chimica Acta, 2006, 89, 1090-1104. ISSN: 0018-019X
  2. Synthesis and Electronic Spectroscopy of Bromo Carbazoles. Direct Bromination of N- and C-Substituted Carbazoles by N-Bromosuccinimide and N-Bromosuccinimide – Silica Gel System. María B. Ponce, Franco M. Cabrerizo, Sergio M. Bonesi* and Rosa Erra-Balsells. Helvetica Chimica Acta, 2006, 89, 1123-1139. ISSN: 0018-019X
  3. Reactivity of Conjugated and Unconjugated Pterins with Singlet Oxygen (O2 (1Δg)): Physical Quenching and Chemical Reaction. Franco M. Cabrerizo, M Laura Dántola, Gabriela Petroselli, Alberto L. Capparelli, Andrés H. Thomas, André M. Braun, Carolina Lorente* and Esther Oliveros*. Photochemistry and Photobiology, 2007, 83: 526–534. ISSN: 0031-8655
  4. A Large Entropic Term due to Water Rearrangement is Concomitant with the Photoproduction of Anionic Free-base Porphyrin Triplet States in Aqueous Solutions. Gabriel O. Andrés, Franco M. Cabrerizo, Víctor Martínez-Junza, Silvia E. Braslavsky* Photochemistry and Photobiology, 2007, 83: 503–510. ISSN: 0031-8655
  5. The photophysics of nitrocarbazoles used as UV-MALDI matrices: Comparative spectroscopic and optoacoustic studies of mononitro- and dinitrocarbazoles. Sergio M. Bonesi, Mariana Mesaros, Franco M. Cabrerizo, María A. Ponce, Gabriel M. Bilmes* y Rosa Erra-Balsells*. Chemical Physics Letters. 2007, 446, 49-55. ISSN: 0009-2614
  6. Photosensitization of 2'-deoxyadenosine-5'-monophosphate by pterin. Gabriela Petroselli, Rosa Erra-Balsells, Franco M. Cabrerizo, Carolina Lorente, Alberto L. Capparelli, André M. Braun, Esther Oliveros*, Andrés H. Thomas*. Organic and Biomolecular Chemistry, 2007, 5, 2792-2799. ISSN: 1477-0520
2004-2005
  1. Generation of Reactive Oxygen Species during the Photolysis of 6-(hydroxymethyl)pterin in alkaline aqueous solutions. Franco M. Cabrerizo, Laura Dántola, Gabriela Petroselli, Carolina Lorente and Andrés H. Thomas*, Rosa Erra-Balsells and Alberto L. Capparelli*. Helvetica Chimica Acta, 2004, 87, 349-365. ISSN: 0018-019X
  2. Photooxidation of Pterin in Aqueous Solutions: Biological and Biomedical Implications. Franco M. Cabrerizo, María L. Dántola, A. Thomas, C. Lorente, A. Braun, E. Oliveros* and A. L. Capparelli*. Chemistry and Biodiversity; Wiley-VCH Verlag Chimica Helvetica Acta; Zürich, 2004, 1, 1800-1811. ISSN: 1612-1872
  3. Photochemical behaviour of 6-Methylpterin in Aqueous Solutions: Generation of Reactive Oxygen Species. Franco M. Cabrerizo, Carolina Lorente, Mariana Vignoni, Romina Cabrerizo, A. Thomas* y A. L. Capparelli*. Photochemistry and Photobiology, 2005, 81: 793–801. ISSN: 0031-8655
  4. Substituent effects on the photophysical properties of pterin derivatives in acidic and alkaline aqueous solutions. Franco M. Cabrerizo, Gabriela Petroselli, Carolina Lorente, Alberto. L. Capparelli, Andrés H. Thomas*, André M. Braun and Esther Oliveros*. Photochemistry and Photobiology, 2005, 81: 1234–1240. ISSN: 0031-8655
  5. Electronic spectroscopy of the β-carboline derivatives nitronorharmanes, nitroharmanes, nitroharmines and chloroharmines in homogeneous media and solid matrix. Olga I. Tarzi, María A. Ponce, Franco M. Cabrerizo, Sergio M. Bonesi* and Rosa Erra-Balsells*. ARKIVOC, 2005, Part XII, 295-310. ISSN: 1424-6376
2002-2003
  1. Decamolybdodicobaltate (III) heteropolyanion: Structural, Spectroscopical, Thermal and Hydrotrating Catalytic Properties. C. Cabello*, F. Cabrerizo, A. Alvarez and H. Thomas. J. Mol. Catal. A: Chem., 2002, 186, 89-100. ISSN: 1381-1169
  2. Photochemical behaviour of folic acid in alkaline aqueous solutions and evolution of its photoproducts. Andrés H. Thomas, Gustavo Suárez, Franco M. Cabrerizo, Fernando S. García Einschlag, Raúl Martino, Claudio Baiocchi, Edmondo Pramauro and Alberto L. Capparelli*. Helvetica Chimica Acta, 2002, 85, 2300-2315. ISSN: 0018-019X
2000-2001
  1. Study of the photolysis of 6-carboxypterin in acid and alkaline aqueous solutions. Gustavo Suárez, Franco M. Cabrerizo, Carolina Lorente, Andrés H. Thomas and Alberto L. Capparelli*. Journal of Photochemistry and Photobiology A: Chemistry, 2000, 132, 53-57. ISSN: 1010-6030
  2. Study of the photolysis of folic acid and 6-formylpterin in acid aqueous solutions. Andrés H. Thomas, Gustavo Suárez, Franco M. Cabrerizo, Raúl Martino and Alberto L. Capparelli*. Journal of Photochemistry and Photobiology A: Chemistry, 2000, 135, 147-154. ISSN: 1010-6030
  3. Al2O3-supported Mo6-Anderson Heteropoly oxomolybdates: Adsorption Studies for X= TeVI , AlIII, CoIII , and NiII by DRS Spectroscopy end TPR Analysis. Carmen I. Cabello*, Irma L. Botto*, F. Cabrerizo, María G. González and Horacio J. Thomas. Adsorption Science & Technology, 2000, 18 (7) 591-608. ISSN: 0263-6174
  4. Photochemistry of 6-formylpterine in alkaline medium. A. Thomas, G. Suarez, F. Cabrerizo, and A.L. Capparelli*. Helvetica Chimica Acta, 2001, 84 3849-3860. ISSN: 0018-019X